piRNAs and Their Functions in the Brain
نویسندگان
چکیده
منابع مشابه
piRNAs and Their Functions in the Brain.
Piwi-interacting RNAs (piRNAs) are the non-coding RNAs with 24-32 nucleotides (nt). They exhibit stark differences in length, expression pattern, abundance, and genomic organization when compared to micro-RNAs (miRNAs). There are hundreds of thousands unique piRNA sequences in each species. Numerous piRNAs have been identified and deposited in public databases. Since the piRNAs were originally ...
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15 صفحه اولBiogenesis and germline functions of piRNAs.
Small interfering RNAs and microRNAs are generated from double-stranded RNA precursors by the Dicer endonucleases, and function with Argonaute-family proteins to target transcript destruction or to silence translation. A distinct class of 24- to 30-nucleotide-long RNAs, produced by a Dicer-independent mechanism, associates with Piwi-class Argonaute proteins. Studies in flies, fish and mice impl...
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ژورنال
عنوان ژورنال: International Journal of Human Genetics
سال: 2016
ISSN: 0972-3757
DOI: 10.1080/09723757.2016.11886278